Migratory Capacity Subsets with Distinct Responsiveness and CD27 Dissects Mature NK Cells into Two
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منابع مشابه
CD27 defines phenotypically and functionally different human NK cell subsets.
The absence of the TNF-receptor family member CD27 marks the stable acquisition of cytolytic effector functions by both CD4(+) and CD8(+) T cells. We found that the majority of circulating human NK cells was CD27(-). These cells were largely CD56(dim), contained high levels of perforin and granzyme B, and were able to exert strong cytotoxic activity. In contrast, circulating CD27(+) NK cells we...
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